Peter the GreatSt. Experts from St. Petersburg Polytechnic University (SPbPU) have developed new antitumor compounds based on thienopyrimidines to increase the effectiveness of cancer treatment. The results of the efficacy study showed that the number of melanoma lung metastases was reduced 10-fold compared to the control group and 4-fold compared to paclitaxel, the most used anti-cancer drug. St. Petersburg Polytechnic University told socialbites.ca about this. The research is carried out within the framework of the “Priority 2030” program of the Russian Ministry of Education and Science.
Histological analysis revealed no pathological changes in the major organs of the animals after treatment. The study also showed that these compounds were safe in healthy animals.
Melanoma is the most dangerous form of skin cancer and can spread to other organs. Chemotherapy remains one of the main therapeutic approaches in the treatment of many types of cancer, including metastatic melanoma. However, cancer cells develop resistance to this, so the search for new drugs that will specifically fight cancer cells without harming the body is an urgent task today.
“The developed compounds showed their effectiveness in the treatment of melanoma metastases in the lungs. In addition, the low toxicity of the drugs to healthy cells and tissues opens up ample opportunities for further research and study of new effective antitumor agents. At this stage, the eponymous National Medical Center at St. Petersburg Polytechnic University We carry out joint research with the Research Oncology Center. “We thank Petrov for a more detailed study on the safety of the obtained compounds,” Alexander Timin, head of the laboratory of nano- and micro-encapsulation of biologically active substances at NN Petersburg Polytechnic University, told socialbites.ca. said.
Previously in Russia was created A method of diagnosing depression using EEG of the brain.
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Source: Gazeta

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