Understanding Acne, Hyperandrogenism, and Hormonal Evaluation: A Comprehensive Perspective

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In about 15 percent of acne cases, it may be appropriate for a patient to consult a gynecologist or a gynecologist-endocrinologist. This referral is typically considered when clinicians suspect hyperandrogenism, a condition characterized by elevated levels of male sex hormones. A dermatologist at the SberZdorovye network, Svetlana Petrova, noted this possibility in discussions with socialbites.ca.

She emphasized that such referrals are usually considered when acne is accompanied by other signs of hyperandrogenism. Common accompanying symptoms include hirsutism, which is excessive body hair growth, and androgenic alopecia, a pattern of hair loss on the scalp. Irregular menstrual cycles can also be a clue. When these symptoms are present, doctors may recommend blood tests and a consultation with a relevant specialist to rule out other conditions, such as polycystic ovary syndrome (PCOS).

Elevated male hormone activity can arise from issues in other endocrine organs, including the thyroid gland or pituitary gland. Less commonly, androgen-secreting tumors of the ovaries or adrenal cortex, or the use of androgens and anabolic steroids, may contribute to the hormonal picture.

In many acne cases, routine hormone testing may not be necessary. Acne is a chronic skin disease driven by genetic factors that influence how actively the sebaceous glands work and produce sebum. The redness and inflammation seen in acne can reflect absolute hyperandrogenism, where the body makes too much male hormone, or relative hyperandrogenism, which is more common. In the latter scenario, the sebaceous glands respond more strongly to normal hormone levels because receptor sensitivity is increased.

According to the dermatologist, effective acne management rests on two main pillars: proper skin care and appropriate therapy, whether topical or systemic. Basic skin care includes gentle cleansing, moisturization, and sun protection. Products should be chosen on an individual basis, taking into account the specific condition and characteristics of the patient’s skin. For mild to moderate acne, treatment primarily involves external medications such as creams and gels. In more advanced cases, a clinician may prescribe additional systemic therapy.

Chronic insomnia in women can sometimes accompany hormonal shifts related to the ovarian cycle, but it is important to explore sleep health and overall well-being as part of a comprehensive approach to treatment. The goal is to support both skin health and hormonal balance through coordinated care among dermatologists, gynecologists, and endocrinologists when needed. (Attribution: Svetlana Petrova, dermatologist at the SberZdorovye network)

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