In Miami, United States, two newborns faced brain injury linked to a maternal coronavirus infection during pregnancy. The finding comes from a collaborative study conducted by the University of Miami Health System and the Miller School of Medicine at the University of Miami, offering important insights into how a maternal illness may impact a child’s development. (attribution: University of Miami Health System; Miller School of Medicine)
According to the study, one infant passed away at about 1.1 years old. This outcome underscores the serious nature of the condition and the need for ongoing research into neonatal health following maternal COVID-19 exposure.
The researchers report that the virus appeared to reach the developing child via the placenta during gestation, potentially leading to brain injuries in the newborns. Interestingly, both infants tested negative for active COVID-19 at birth or thereafter, yet their blood showed high levels of antibodies, indicating in utero exposure and an immune response to the virus. (attribution: University of Miami Health System; Miller School of Medicine)
Medical teams noted that both mothers contracted the virus during the second trimester, with one of them experiencing a reinfection in the third trimester. The timing of infection is relevant to understanding potential risks for fetal brain development and the overall pregnancy outcome. (attribution: University of Miami Health System; Miller School of Medicine)
Lead investigator Professor Ali Saad from the Miller School of Medicine described the placental examinations performed in these cases. The analysis revealed pathological changes consistent with the effects of the virus on placental structure and function, which researchers believe may contribute to the neonatal brain findings observed in these infants. (attribution: University of Miami Health System; Miller School of Medicine)
Experts emphasize that when a pregnant person contracts SARS-CoV-2, there can be downstream implications for the child’s neurodevelopment. Ongoing studies aim to clarify which factors most strongly influence outcomes and how best to protect both mother and baby during pregnancy. (attribution: University of Miami Health System; Miller School of Medicine)