Hypercortisolism: Signs, Risks, and When to Seek Medical Care

When the body experiences stress, the adrenal glands release a hormone called cortisol. An excess of cortisol can contribute to fat buildup around the midsection, darkening of skin in skin folds, and episodes of heightened alertness. This portal quotes Dr. Peter and references insights from Professor Oksana Drapkina, who leads the National Research Center for Therapeutic and Preventive Medicine and serves as chief freelance specialist in therapy and general medical practice for the Ministry of Health of Russia. She holds the title of Honorary Doctor of the Russian Federation and is a respected member of the Russian Academy of Sciences.

People may notice signs that point toward elevated cortisol levels, such as fat accumulation under the chin, around the neck, and along the shoulders, which can create a moon-shaped face in many individuals. Extra pigmentation in skin folds can also reflect higher cortisol. In women, elevated cortisol may disrupt menstrual cycles and increase hair growth on the chest, back, and face.

Only a clinician can diagnose hypercortisolism. If a person has persistent symptoms or unusual changes in weight, skin, or hair, a medical evaluation at a hospital or clinic is essential.

One of the most serious risks associated with sustained high cortisol is a sudden rise in blood pressure, sometimes accompanied by vomiting, abdominal pain, or fainting. This adrenaline surge can place a heavy burden on the heart and kidneys and, in severe cases, may be life-threatening.

Earlier commentary noted fatigue that can occur at morning or evening times, which can be linked to hormonal imbalances. A healthcare professional can assess these symptoms within a broader health context and determine appropriate tests or next steps. (citation: clinical guidance from the National Research Center for Therapeutic and Preventive Medicine and allied medical experts).

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