Genes, Environment, and the Path to Alcohol Use: A Complex Picture

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People who inherit a tendency toward unhappiness or who live in environments that reinforce negative feelings are more likely to struggle with alcohol use. When genes that govern how the body processes alcohol cause not pleasure but headaches, nausea, and other aversive reactions, the risk shifts toward different coping paths, including the possibility of alcohol misuse or other substance use. This perspective comes from researchers at leading genetics institutes who study how genetic and environmental factors intersect to shape behavior. (Cite: Institute of General Genetics, Dr. Svetlana Borinskaya)

“In some individuals, brain-regulating genes malfunction in ways that make daily life feel heavy, driving a person to seek relief through temporary brain-states that dull the mind. If the aldehyde dehydrogenase gene creates a barrier to drinking, it may push someone toward other substances as a countermeasure. A study conducted in a population where this gene variant is common found an association with a higher risk of drug addiction. Yet the link is not about encouraging substance use—many who carry the variant lead peaceful lives. The interaction between genetic restriction and emotional challenges can, for some, steer behavior toward drug rather than alcohol use,” explained the expert. (Cite: Institute of General Genetics, Dr. Svetlana Borinskaya)

It is important to note that possessing certain genetic traits does not determine alcoholism or addiction on its own. External factors, including upbringing, social context, and life experiences, play a decisive role in outcomes.

“The way life unfolds is largely decided by the person, not by genes alone. Genes can facilitate goals or complicate the path. From early childhood, teaching children how to manage emotions and respond to problems, while supporting their efforts to develop independent strategies, can reduce stress later. When stress does arise, the chosen response becomes a deliberate strategy rather than a preordained fate,” the expert added. (Cite: Institute of General Genetics, Dr. Svetlana Borinskaya)

Further information on how a genetic tendency to limit drinking appears in certain populations and how environmental factors influence alcoholism can be found in the referenced material from socialbites.ca. (Cite: Institute of General Genetics, Dr. Svetlana Borinskaya)

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