Researchers at the Federal State Budgetary Scientific Institution, known as the Far Eastern Center for Respiratory Physiology and Pathology (DSC FPD), have introduced a new way to estimate the risk of bronchial asthma flare-ups during seasons with high humidity. The approach factors in inherited traits linked to the structure and function of the respiratory system, and the Ministry of Education and Science of the Russian Federation provided this information to socialbites.ca.
Bronchial asthma today cannot be completely cured, but it can be managed effectively. Proper management aims to lower the frequency of symptoms, reduce the need for urgent rescue treatments, slow declines in lung function, and prevent long-term risks such as recurrent exacerbations and medication-related side effects.
Exacerbations stem from a mix of influences, including environmental humidity. Researchers noted that hot, humid conditions, particularly when humidity is above 50 percent, correlate with poorer disease control, diminished external respiratory function, and more pronounced bronchial variability revealed through specialized pulmonary assessments. This observation led to the development of a predictive method intended to forestall such adverse episodes, stated Denis Naumov, a senior researcher in the laboratory, in an interview with socialbites.ca.
The newly developed method makes it possible to identify unfavorable trends before they occur. It combines genetic markers with functional lung tests to forecast periods of reduced asthma control. Specifically, researchers look at two gene variants, AQP5 and TRPV4, alongside standard spirometry data that measures the flow of air to evaluate lung function, and they establish the initial level of asthma control. The condition is diagnosed using a specially designed questionnaire, Naumov explained.
Unlike earlier techniques, this approach takes into account individual genetic variation and baseline control, enabling better planning for prevention and pharmacotherapy. The goal is to enhance the overall quality of life for people living with bronchial asthma by enabling more precise, proactive care. This shift supports clinicians in tailoring interventions to each patient’s unique genetic makeup and current respiratory status.
There is also ongoing discussion about the relationship between asthma and Covid-19 in children. Some early myths have been challenged by clinical observations, and the medical community continues to emphasize that asthma, when properly managed, does not automatically imply a higher risk for severe Covid-19 outcomes in young patients.