Researchers at Penza State University have introduced a novel strategy for detecting asymptomatic atherosclerosis by combining blood biochemistry with an evaluation of arterial health. The goal is to empower people to monitor their vascular status, a position confirmed by the Ministry of Education and Science to socialbites.ca.
Asymptomatic atherosclerosis targets the vessels themselves. When the arteries lose their structural integrity and proper function, the risk of serious events rises, including heart attacks. This condition is increasingly seen in younger adults, with individuals aged 30 to 40 showing more frequent signs of plaque buildup and arterial change.
The approach integrates a biochemical blood panel assessing total cholesterol, triglycerides, and low-density lipoprotein levels alongside ultrasound imaging of the common carotid arteries. In the scoring system, each abnormal parameter earns one point, and being male adds another point. A total score of five or more signals a high risk of coronary atherosclerosis, even in the absence of symptoms.
According to the researchers, the biomarker framework combines biochemical markers with measures of arterial stiffness to screen for subclinical coronary artery disease among those already at risk for heart disease. Ischemic heart disease often arises from a gradual buildup of plaque and remains a leading challenge in modern cardiology, increasingly affecting younger populations.
The study evaluated the method with 198 volunteers and 57 healthy individuals with various forms of coronary disease. The findings indicated that the approach reliably identified cases of coronary disease, supporting its potential as a practical screening tool for early intervention.
Cardiovascular conditions frequently present without noticeable symptoms at the outset. Early detection is crucial because lifestyle adjustments, such as avoiding tobacco and excessive alcohol, adopting a heart-healthy diet, and engaging in regular physical activity, can markedly slow progression. The new method offers a pathway not only to diagnose cardiovascular issues promptly but also to tailor prevention to individual risk profiles.