The risk of miscarriage increases with the use of benzodiazepine medications during pregnancy. This has been shown by a study published in the journal. JAMA Psychiatry.
Scientists from National Taiwan University in Taipei analyzed data from three million pregnancies of nearly two million women. Information was collected from 2004 to 2018. Miscarriage occurred in 4.4% of cases.
Researchers have found that the risk of miscarriage increases while taking benzodiazepines during pregnancy. The odds of miscarriage were 1.3 to 2.5 times higher in women taking benzodiazepines than in those not taking benzodiazepines. The authors also considered other factors that affect the risk of miscarriage. Benzodiazepines have hypnotic, relaxing, anti-anxiety and anticonvulsant effects.
“These findings suggest caution should be exercised when using benzodiazepines in early pregnancy. The results of this study also provide data that will help clinicians make informed decisions about treating mental health and sleep disorders in pregnant women,” the scientists wrote.
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