Researchers from the Wilmer Eye Institute at the University of Johns Hopkins revealed that there is a new connection between the destruction of the barrier between reduced blood sugar (hypoglycemia) attacks and the retina of the eye. This discovery helps to understand how diabetic retinopathy develops – one of the most dangerous complications of diabetes can lead to irreversible vision loss. Published in İş Magazine Science Translation Medicine (STM).
Scientists have found that HIF protein (hypoxia -related factor) accumulated during hypoglycemia in retinal cells. The most important mechanism for the preservation and nutrition of eye tissue initiates a series of reactions that cause excessive growth and blood vessels that destroy the hemato-retinal barrier.
In a non -experiment on mice, hypoglycemia has shown that only an increase in HIF level in animals with diabetes. This provokes the leakage of retinal vessels and potential vision damage. This effect was not observed in healthy mice.
In addition, the researchers tested the experimental medicine 32-134D that crushed HIF. There was a decrease in the prevention of the destruction of the vascular barrier in diabetic mice that injured the drugs of hypoglycemia attacks.
The leading author of the study. Acrite Sodhi explains why our data has started intense glucose control or sharp fluctuations in blood sugar, and may encounter a deterioration in the case of vision, Sod “This also confirms that drugs affecting the HIF have the potential in the prevention and treatment of diabetic retinopathy.”
Previously, scientists learned Estimate the age of the onset of Alzheimer’s disease.
What are you thinking?
Source: Gazeta
Barbara Dickson is a seasoned writer for “Social Bites”. She keeps readers informed on the latest news and trends, providing in-depth coverage and analysis on a variety of topics.