A group of international scientists from the United States, Israel, Portugal and other countries had a double effect among the drugs of Freanzumab’s migraine. It turned out that the vehicle not only reduced the frequency of headache attacks, but also eliminated depression. The study was published scientifically magazine Jama neurology.
It is known that migraine and depression are dependent: depression is 2-4 times more common in migraine suffering. Both cases may be caused by the imbalance of serotonin and glutamine.
Freenezumab belongs to the monoclonal antibody class that blocks the CGRP protein, which plays a role in the development of migraines.
540 patients from 12 countries attended a test of 28 weeks (including US and EU countries). Subcutaneous Freanzumab (225 mg) injections have decreased a decrease in the number of monthly migraine cases and a decrease in depressive symptoms compared to placebo.
Scientists propose two mechanisms: a direct effect on general neurochemical processes and a psychological situation of patients due to lack of pain.
The results reveal new opportunities for the treatment of complex cases where migraine is combined with depression. However, researchers emphasize that additional studies are needed to understand the exact mechanisms of the drug.
Previously, scientists provenThis orgasm effectively helps to overcome migraine.
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Source: Gazeta
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