Researchers from the University of Jones Hopkins identified three different “zombies” subtypes of the skin, which is different in shape and function. The selective effect on them will help fight diseases such as cancer. Research Results published In Science Advances magazine.
Unlike the ordinary ones, “zombie cells” are naturally not “self-stir” in the body. They stop division due to damage or stress, remain in tissues and cause inflammation. So far, all aging cells in the same type of tissue have been believed to be approximately the same. However, as Jud Fillip’s work explained, aging skin cells can be moved to one of three different states.
Scientists team analyzed skin fibroblasts (cells forming a tissue fabric) in samples of 50 healthy donors between the ages of 20 to 90 years. With the help of machine learning and visualization technologies, the researchers examined 87 physical characteristics of each cell and divided them into groups.
As a result, they found fibroblast of 11 forms and sizes, three of which were characteristic of aging cells. One of the subtypes called C10 was common, especially in the elderly.
Scientists say that further studies will help determine which subtypes can be useful. This opens opportunities for the development of drugs that will deliberately eliminate harmful aging cells and minimize side effects.
In addition, the point effect on cell aging can be an important tool in the treatment of cancer. Some modern therapies cause aging of cancer cells to stop the growth of the tumor, but their savings can lead to inflammation and additional load in the patient’s immune system. According to scientists, new approaches to treatment can solve this problem.
Previously, scientists Defined Hidden mechanisms of rare genetic diseases in children.
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Source: Gazeta
Barbara Dickson is a seasoned writer for “Social Bites”. She keeps readers informed on the latest news and trends, providing in-depth coverage and analysis on a variety of topics.