Researchers from the Massachusetts Institute of Technology have developed an innovative drug distribution method that allows you to apply high doses with less discomfort. Methods are based on the introduction of the drug as a suspension of small crystals that form a stable “warehouse olan under the skin after the injection – storage of a drug that can release active substances for months and even years. Published in İş Magazine Nature Chemical Engineering.
Unlike existing injection drugs scattered in tissues and requiring repeated application every three months, the new technique directly provides an intense “warehouse” formation under the skin. This was possible by the use of a biomocratic gasolinezoate solvent that prevented the rapid mix of drug crystals with biological fluids and allowed them to be collected independently in a compact structure.
In addition, the addition of a small amount of polymer (less than 1.6% of the mass) allows you to check the release rate of the drug.
During the experiments on rats, scientists proved that the drug maintained stability and slowly released for three months. Moreover, at the end of the experiment, 85% of the drug remained in the “warehouse ,, which showed the possibility of action for more than a year.
If necessary, the tank can be removed surgically, which makes the method safe and flexible in use.
This technology can greatly simplify the use of long -term contraceptives and other drugs requiring regular injection. In addition, due to the possibility of using a thin needle, the presentation of the drug becomes less painful.
“We have shown that it is possible to release the drug in a controlled and long way from a few months to several years, Mass
Now researchers are doing additional premium clinical studies to adapt clinical use method.
Previously, scientists To create The way to double the chance of protecting the erectile function after removing prostate cancer.
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Source: Gazeta

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