NI Vavilov found that F. Prausnitzii could be used to treat depression at the Microorganisms Laboratory of the General Genetic Institute, named after Ras. The project manager, Senior Researcher Olga Averina, was told about this Gazeta.ru.
The brain and intestines are inseparable and in the intestines of the problem, this affects the work of the entire organism. As an active participant on the intestinal axis, intestinal microflora not only affects intestinal functions, but also stimulates the development of the central nervous system in the perinatal period and interacts with the highest nerve centers, which causes various pathologies including depression and cognitive disorders.
With the development of depression in the intestines, the number of B. Prausnitzii bacteria is reduced, thus a biobelirtic task of the disease. It is possible to improve depression, according to scientists, it is possible to increase the number of intestines.
“Research on patients with mouse model and depression of depressed behaviors has enabled us to choose a positive effect on a decrease in both the animal and people’s depressive symptoms for 28 days. After receiving the drug in patients, a significant decrease in depression and anxiety manifestation was observed, stool normalization, calm and cognitive functions increased an increase. ”
The insertion of a probiotic drug based on a lactobasillic strain affected the composition of the intestinal microbiota. In humans, the number of beneficial bacteria, including F. Prausnitzii, has increased.
“Therefore, the lactobacill strain, which has a positive effect on a depressive condition, may be recommended as additional (adjuvant) treatment tools for probiotic psychobiotics and depressive disorders. We are bacteria of F. Prausnitzii species, which are considered potential psychobiotics. In the future, we will select strains with antidepressant properties. Since F. Prausnitzii is a solid anaerob (oxygen is destructive for these bacteria), it is necessary to choose a probiotic birth form for antidepressant treatment. ”
The project was supported by RNF grant.
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Source: Gazeta
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