American scientists from the Massachusetts Institute of Technology have developed a new method to save a person’s life during an opioid overdose. The study was published in the scientific journal magazine Device.
The team created an implantable sensor about the size of a gumdrop. The device is inserted under the skin and monitors heart rate, breathing rate and other vital signs. When the device detects signs of overdose, it releases a dose of naloxone into the body.
Naloxone acts as an opioid antagonist. It can bind to opioid receptors and block the effects of opioids, including heroin and fentanyl. The medication is usually given by injection or nasal spray, and normal breathing is restored within minutes of administration.
The study found that fentanyl first causes a decrease in heart rate, followed by a rapid slowing of breathing. By measuring how these signals changed, scientists were able to calculate when to administer naloxone.
In animal tests, the implant was able to reverse the effects of overdose in 96% of cases.
The team plans to test the device in humans within the next five years.
Previously in the USA developed Nasal spray for treating drug overdose.
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Source: Gazeta

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