American scientists from the University of Virginia have developed materials that could form the basis of transplant production using a 3D printer. The study was published in the scientific journal magazine Nature Communications (NatComms).
The team created a bioprinting method called digital assembly of spherical particles (DASP). It involves embedding pieces of biomaterial in a supporting matrix to create three-dimensional structures that provide environments for cell growth. These structures are called “voxels.”
The particles are polymer hydrogels that mimic human tissue by changing the arrangement and chemical bonds of individual monomer molecules, which are linked in chains to form networks. Inside the particles are living human cells.
“Our new hydrogel particles represent the first functional voxel we have ever made. This voxel, which precisely controls the mechanical properties, can serve as one of the fundamental building blocks for our future printed structures,” said study co-author and graduate student Jinchang Zhu.
According to the authors of the development, hydrogel bioinks are less toxic and more biocompatible with cells compared to analogues. Scientists believe that the material could be a breakthrough and become the basis for voxelized bioprinting of organs for implantation.
Previous researchers It was announced about a breakthrough in diagnosing donor organ survival.
Source: Gazeta
Barbara Dickson is a seasoned writer for “Social Bites”. She keeps readers informed on the latest news and trends, providing in-depth coverage and analysis on a variety of topics.