New findings link COVID-19 infection during pregnancy to an increased risk of preeclampsia
Researchers from a major University in the United States have uncovered evidence that coronavirus infection during pregnancy may trigger preeclampsia, a dangerous rise in blood pressure that can threaten both mother and child. The study, published in Clinical and Translational Immunology, emphasizes the potential impact of SARS-CoV-2 on maternal health and fetal well-being.
In their investigation, scientists compared placental tissue from unvaccinated women who tested positive for SARS-CoV-2 within 15 days of giving birth with tissue from unvaccinated women who were not infected. Using advanced digital spatial profiling, which relies on high-resolution cell imaging, the team observed disruptions in placental function. Specifically, the viral infection appeared to alter the genomic architecture of cells essential for delivering blood flow and nutrients to the developing fetus.
The research reinforces a close connection between COVID-19 and preeclampsia, a common and serious pregnancy complication associated with dangerously high blood pressure for both mother and baby. The study also identified molecules in the placenta that may become targets for future research aimed at unraveling the mechanisms behind this association. These molecular markers could guide early detection and inform potential therapeutic approaches for pregnant people affected by the virus.
Overall, the findings highlight the importance of preventive strategies, careful monitoring, and further study of how SARS-CoV-2 interacts with placental biology. As scientific understanding evolves, clinicians may gain better tools to reduce risk and protect maternal and fetal health in communities across North America.
For expectant parents and clinicians alike, staying informed about vaccination guidance and infection prevention remains essential. Ongoing research will continue to clarify how viral infections influence placental development and pregnancy outcomes, ultimately shaping safer care practices for pregnancies in the era of COVID-19.