Cardiac benefits of leg muscle strength after heart attack: insights from Kitasato University

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Recent findings from researchers at Kitasato University in Japan indicate that stronger hip and leg muscles may be linked to a lower risk of heart failure. The study, summarized in the European Journal of Preventive Cardiology, examined muscle strength and its relationship to cardiac outcomes in a large group of individuals with prior heart events. The results suggest a meaningful connection between lower body strength and the future health of the heart, offering new angles on how physical fitness can influence cardiovascular risk over time.

In this long-term study, investigators assessed the strength of the quadriceps and several other leg muscles in more than a thousand participants who had experienced heart attacks. Over a four-year follow-up period, the data showed that for every five percent increase in quadriceps strength, there was an approximate eleven percent reduction in the risk of developing heart failure. Heart failure here refers to the heart’s diminished ability to supply enough blood to meet the body’s needs, a condition that can arise after a heart attack when the heart’s pumping action is compromised. These findings underscore the potential protective effect of leg muscle strength on cardiac function in the years following a cardiac event.

Why might stronger leg muscles influence heart health in this way? One explanation lies in how the body uses and distributes energy during daily activities and physical stress. When leg muscles are robust, the body relies less on the heart to maintain blood flow during exertion, potentially reducing the workload on the heart over time. Additionally, a trained lower body may improve overall circulation, metabolic health, and insulin sensitivity, factors that contribute to heart health. The researchers note that muscle strength could be a marker of overall fitness and a predictor of better cardiovascular remodeling after a heart insult, helping to slow adverse changes in the heart muscle discovered in imaging and clinical assessments. In practical terms, maintaining leg strength might help the heart adapt more efficiently to the demands of daily life, which could translate into fewer episodes of heart strain and a lower likelihood of heart failure developing down the line.

Beyond the primary findings, the study sheds light on the broader relationship between muscle health and heart function. It emphasizes that recovery after a heart attack is not solely about medical interventions but also about maintaining physical conditioning. Regular, progressive resistance training for the lower body could play a role in supporting heart health by promoting favorable changes in muscle mass, vascular function, and metabolic regulation. These insights align with a growing body of evidence that physical activity and strength training contribute to a resilient cardiovascular system, particularly in people with a history of heart disease. Clinicians may consider incorporating leg-strength assessments into post-heart-attack care plans and recommending targeted exercises that safely build quadriceps and other lower-body muscles, all while accounting for each patient’s unique medical history and recovery trajectory.

Researchers also explored the potential hormonal and biochemical pathways that might connect muscle strength with cardiovascular outcomes. Prior studies have highlighted factors released during physical activity that influence brain and body function, including compounds that modulate vascular health and energy metabolism. While the precise mechanisms require further study, the pattern suggests that a physically active lifestyle—with emphasis on leg strength—could foster a cascade of physiological effects that support the heart and brain alike. These connections may help guide future interventions aimed at reducing heart failure risk following a heart attack, offering a practical path for patients to improve long-term outcomes through structured exercise and rehabilitation programs. This line of inquiry continues to evolve, with ongoing research aimed at clarifying how muscle quality, metabolic health, and hormonal responses work together to sustain cardiovascular resilience over time.

In a broader context, the evidence points to a simple, actionable message: building and preserving lower-body strength may yield tangible benefits for heart health, especially after a cardiac event. Individuals recovering from a heart attack can work with healthcare providers to design safe, progressive plans that enhance quadriceps and leg muscle strength while monitoring heart function. Such programs, when tailored to the patient, could complement medical therapies and lifestyle modifications, helping to reduce the chance of heart failure and support a more robust quality of life. The interplay between muscular fitness and heart health is a dynamic field, and these findings contribute a meaningful piece to the puzzle of how to optimize recovery and long-term cardiovascular well-being for people in Canada, the United States, and beyond.»

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