Biomarkers on Baby Skin May Predict Future Allergies

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Scientists have identified that special substances on infants’ skin can help gauge the future risk of food allergies. The findings were published in the Journal of Allergy and Clinical Immunology (JACI) [Source: JACI].

For the study, researchers collected skin cells using adhesive tapes applied to the forearms of two‑month‑old babies. The tape captured surface molecules that remained on the band and could be analyzed later in the lab.

The results show that certain proteins, microbial communities, and oils present on the skin of babies who later develop atopic dermatitis or food allergies are not found in those who stay healthy. Scientists believe these skin components could one day be used to predict allergy risk early, enabling more proactive prevention strategies from a very young age.

There is ongoing work to test anti-inflammatory fatty acid creams in newborns. The goal is to determine whether these products can lessen the likelihood of allergic reactions in babies who are at higher risk.

Past research has linked early life factors to later health outcomes. For instance, childhood obesity has been associated with an increased risk of developing multiple sclerosis in later years, underscoring how early biology can shape future health trajectories [Source: JACI].

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