A group of specialists within the plastic surgery field report that grafting autologous fat into the female genital area may enhance sexual function by promoting collagen synthesis, angiogenesis, and the expression of estrogen receptors. Findings from this work were presented in the Journal of Aesthetic Surgery (ASJ) and discussed within a clinical setting aimed at improving female sexual health.
Autologous fat, often sourced from the patient, is valued for its compatibility and relatively low risk of rejection. When used in tissue transplantation, it can provide a living graft that may contribute to improved tissue perfusion and regenerative outcomes. Autologous adipose tissue is also known to contain adipose-derived stem cells, which can support microcirculation and tissue rejuvenation through restorative processes.
Clinicians proposed that vulvovaginal infusion of such fat grafts could address cases of reduced orgasmic response in some individuals. The study population consisted of ten participants who underwent treatment between 2017 and 2020. Assessments included the Female Sexual Function Index questionnaire along with gynecological examinations to gauge outcomes.
Reportedly, an average of 21.9 milliliters of fat graft was delivered to the vaginal region and 20.8 milliliters to the vulvar and pubic areas. After a six-month period, participants showed a meaningful improvement in sexual satisfaction scores relative to baseline measurements. Histological and immunohistochemical analyses of vaginal tissues indicated increases in neocollagenesis, neoangiogenesis, and the presence of estrogen receptors, suggesting tissue remodeling and hormonal receptor activity as part of the observed effects.
Authors emphasize that these observations warrant careful interpretation and further study to confirm long-term safety, efficacy, and reproducibility across broader populations. The work contributes to ongoing discussions about regenerative approaches in female sexual health and invites additional randomized trials to validate the potential benefits of autologous fat grafting in this context.
Note: The information summarized here reflects reported findings and does not constitute medical advice. Patients should consult qualified healthcare professionals to discuss individual risks, benefits, and alternatives to any proposed procedure. Research cited originates from the Journal of Aesthetic Surgery (ASJ).—(Source attribution: Journal of Aesthetic Surgery, ASJ).