Arsenic exposure through drinking water is a public health concern in many regions, including parts of the United States, India, Taiwan, and Chile. Long-term ingestion of arsenic is linked to a range of health issues, with cancer risk being a prominent concern. Nutrition plays a crucial role in how the body handles toxins like arsenic. In particular, folic acid, also known as vitamin B9, appears to influence arsenic metabolism in the body, and recent findings from a U.S. study suggest that folic acid status can affect immune responses after vaccination in children. This research indicates that adequate folic acid levels may help the body deal with arsenic more efficiently, potentially reducing harmful effects on vaccine antibodies. The study’s observations come from a group of U.S. children who had received the measles vaccine, highlighting a link between urinary arsenic, folic acid levels in the blood, and the strength of measles antibodies, while also considering factors such as age, race, diet, and overall health status.