A research team from the University of Gothenburg and Sahlgrenska University Hospital in Sweden found that being underweight at birth and overweight at age 20 contributed to the development of type 2 diabetes in men at age 59 and younger. Research results published In the journal Diabetologia.
More than 34 thousand Swedes participated in the research. Scientists collected information about the health status of the subjects and recorded their body weight indicators. The researchers also collected data on participants’ birth weight. After this began the phase of observation of the subjects, which lasted more than 30 years.
An analysis of information after 34 years of follow-up showed that those born with low weight were 10 times more likely to develop type 2 diabetes at a young age compared to people born with normal weight (2.5-4.5 kg). In addition, low weight at birth and increased body weight at the age of 20 also affected the risk of contracting this disease, increasing the likelihood of the disease by 27%.
The authors of the study noted that such results emerged as a result of correlation analysis, which does not allow a direct cause-effect relationship to be established. They suggested that the metabolic consequences of fetal growth restriction may lead underweight babies to develop traits that allow their bodies to store more fat and develop insulin resistance.
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