Scientists from the University of Traz des Montes and Alto Douro in Portugal have discovered that porcini mushrooms (Boletus edulis) and mushrooms (Agaricus bisporus) have anti-cancer properties. results published In Medical Sciences Forum (MSF).
In the study, researchers examined microRNAs of previously harvested and dried porcini mushrooms (Boletus edulis) and oilseed mushrooms (Agaricus bisporus) using anion exchange chromatography. This method involves separating substances (ions and polar molecules) based on their charge using ion exchange resin. Qualitative and quantitative determination of the purity and quality of reagents, drugs and purification of antibiotics and protein compounds from impurities is carried out using ion exchange chromatography.
The potential anticancer activity of these two mushroom species was evaluated in comparison with chanterelles. It was previously found that chanterelles contain substances that suppress cancer cells.
Scientists discovered unique fractions (fragments) of BEDA and BEDB in the miRNA of porcini mushrooms and ABIA in mushrooms. Evaluation of their effectiveness as tumor suppressors showed that ABIA could reduce the viability of cancer cells at a concentration of 50 μg/ml. Higher doses of ABIA may be more effective at suppressing cancer, but they are cytotoxic to normal cells. The BEDB fraction also showed anticancer properties.
It is stated that further research is needed to determine the mechanisms underlying this antitumor activity.
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