Adam Collins and Martin White are Associate Professors in the Department of Nutrition and Metabolomic Medicine, University of Surrey (UK). said Talk about how people often regain weight after stopping Ozempic and Vegovi (popular weight loss drugs).
Ozempic and Vegovi are called GLP-1 receptor agonists. These are analogues of GLP-1, one of the incretin class hormones produced in the intestines after eating and stimulating insulin production. They also affect the areas of the brain associated with pleasure – specifically the pleasure of eating, reduced appetite.
It is stated that many people stop taking weight loss medications due to the presence of chronic obstructive pulmonary disease and hypertension, as well as side effects. Studies have shown that only 44% of people prescribed such medications continue to take them for three months after receiving the prescription. After one year, only 19% of patients were using GLP-1 receptor antagonists.
In addition, effective weight loss with the help of drugs occurs only due to their constant use. A recent study by British researchers at the University of Liverpool found that stopping Vegovi was associated with participants gaining back more than half the weight they lost. The fact is that after stopping the drug, the level of the GLP-1 hormone decreases sharply, as a result of which the person loses control over appetite.
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