Researchers at Harvard Medical School found that exercise activated anti-inflammatory immune system T cells in mice. results published In Science Immunology.
It is known that physical exercise supports the good functioning of the digestive system, stimulates the cardiovascular and respiratory systems, improves mood and is useful in the treatment of multiple sclerosis, Alzheimer’s and Parkinson’s diseases. The research team sought to find out how exercise affects the immune system (a set of processes that protect the body from infections, toxins and malignant cells).
Scientists analyzed what was happening in the muscle cells in the hind legs of mice that once ran on a treadmill and animals that ran regularly. The scientists then compared these to muscle cells in mice that had received no exercise.
Researchers have found that muscles are exposed to microtrauma as a result of exercise, causing an inflammatory response in the body. This inflammation activates T cells (Tregs). T cells are lymphocytes that have the ability to absorb and destroy foreign antigens. They can recognize cancer cells, viruses, bacteria and fungi. T cells were activated both in mice that ran regularly and in animals that did the exercise (running) only once. Such changes were not observed in rodents leading a passive lifestyle.
Increased T cell activity is accompanied by an improved ability of the immune system to eliminate antigens that protect the body from various diseases.
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