A team of scientists from the Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences (Novosibirsk) announced that antibodies formed after vaccination with Sputnik V cannot cause malfunctions in the body. socialbites.ca was told about this by the press service of the Russian Science Foundation.
During the coronavirus pandemic, vaccines have helped fight the disease. Three of them were created in Russia; the most famous of these was Sputnik V.
Scientists have debunked the myth that vaccination produces catalytic antibodies with pathological activities characteristic of autoimmune diseases (when the immune system attacks healthy cells in the body) such as lupus.
In fact, antibodies are produced against the S protein and its RBD fragment. It neutralizes (immobilizes) the virus. Some of these antibodies hydrolyze (break down) the S protein of SARS-CoV-2, literally “tearing apart” the virus envelope.
Scientists conducted a study on four groups of people, each consisting of 25 participants. The first group consisted of unvaccinated people who had previously contracted coronavirus. The second comes from subjects who were sick and then received the Sputnik V vaccine. Participants in the third group were vaccinated before starting the study but did not get sick, and participants in the fourth control group did not get sick and were not vaccinated.
The researchers analyzed levels of anti-S protein antibodies in the subjects’ blood samples for the presence of catalytic antibodies. It turned out that such pathologically active antibodies were not actually formed as a result of vaccination. This confirms the effectiveness and safety of Sputnik V. In the future, scientists plan to continue research and discover new aspects of the formation of the immune response to viral infections.
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