Doctors at Oxford Hospital Churchill performed the first successful uterus transplant from a living donor. The case was described in an article published by the journal British Journal of Obstetrics and Gynecology (BJOG).
The 40-year-old woman, who already has two children, donated her uterus to her 34-year-old sister. She could not have children because she was born without this organ. This was due to a rare disease: Mayer-Rokitansky-Kuster-Hauser syndrome (MRKH).
It is a congenital malformation characterized by an undeveloped Müllerian duct causing the absence of the uterus. Because the ovaries do not develop from the Müllerian duct, women with MRKC have normal secondary sex characteristics, but these women are not fertile due to the absence of a functional uterus.
In total, the operation took more than 9 hours. The recipient patient plans to have IVF later on. She has kept five embryos and will undergo fertility treatment in central London later this year.
As soon as she joins the family, her womb will be removed so she won’t need immunosuppressants for the rest of her life. Doctors plan to leave the uterus inside the patient for five years before removing it.
Former obstetrician-gynecologist Selikhova judicial Sign of cancer during menstruation.