Some mutations greatly increase the chances of miscarriage, but knowing them can reduce the risk with hormonal drugs or nutritional supplements. Geneticist and lead researcher of MyGenetics Irina Kolesnikova told socialbites.ca about this.
“Mutations in the genes responsible for the synthesis of the female sex hormone estrogen receptors increase the risk of miscarriage. But these risks can be minimized by maintaining a reasonable lifestyle, taking supplements under the supervision of a specialist and, if necessary, hormonal drugs prescribed by a doctor, ”explained Kolesnikova.
The geneticist noted that there are more dangerous mutations. For example, a woman with harmful mutations in the FMR1 gene (which can lead to fragile X syndrome) or a man with a deletion (missing part) in the AZF gene may have serious problems conceiving. Knowing the genetics of such a patient, the doctor can suggest alternative options: artificial insemination, sperm, egg or embryo donation, and adoption.
Fragile X syndrome is associated with mild to moderate mental retardation and behavioral problems in children. The mutation that leads to the development of the disease is seen in about one in two thousand men and one in 259 women.
ancient scientists to solveAfter the birth of a child with the help of artificial insemination, one in five women become pregnant naturally.