Dermatologists from the Dead Sea and Arava Research Center in Israel have proven the anti-aging effect of a cream containing eicosapentaenoic acid (EPA) and cannabidiol (CBD). The results of the research have been published magazine Journal of Cosmetic Dermatology.
Aging is associated with physiological changes in the body, such as loss of collagen. However, this process can be accelerated by several external factors, including pollutants, reactive oxygen species (ROS), ultraviolet radiation, and improper nutrition. All these factors can cause wrinkles, age spots, dry skin, etc. causes it to occur.
Many cosmetic manufacturers claim that their products delay aging. The authors of the study decided to test the effectiveness of two popular ingredients used in cosmetics.
CBD and cannabinoids are components of cannabis. Studies in nude mice have shown that the use of 1% CBD in a cream for 14 days increases skin hydration by upregulating aquaporin-3 levels. CBD also reduces the formation of ROS that cause oxidative stress due to its antipruritic and anti-inflammatory properties, improves hair growth and treats atopic dermatitis and contact dermatitis.
The current study investigated the synergistic anti-aging effects of CBD and EPA. The authors used lab-grown human skin cell cultures that mimic damaged skin. Researchers have found that EPA supplementation enhances the above effects of CBD.
Based on the positive results of the experiments, the scientists tested the cream on 33 people with signs of aging. Various skin parameters were evaluated before and after the procedure for 56 days, and anti-aging gel was applied to the face or other problematic areas. During this time, there was a significant improvement in the condition of the skin, including a 15% reduction in wrinkles.