When the sweetener sucralose is consumed in the body, the activity of immune T cells is reduced. In this respect informs TASS citing the Francis Crick Institute.
This was found in a series of experiments on laboratory rats. In experiments over 12 weeks, a significant but safe amount of sucralose was added to the animals’ food and their condition was monitored.
Apparently, this sweetener is not as biologically inert as previously thought, but has the ability to damage the immune system. In particular, the scientists found that long-term and continuous use of this sweetener led to a decrease in the activation rate of two types of T cells, CD4 and CD8, as well as reduced the strength of their reaction and their reproductive rate. in response to a threat to the body.
Experiments showed that these changes in T-cell behavior made mice more vulnerable to bacterial infections and also reduced immune responses against cancerous tumors. On the other hand, long-term use of sucralose has reduced the likelihood of developing autoimmune diseases and other disorders associated with excessively high immune activity.
Both of these effects have been associated with impaired calcium circulation between the body and T cells. The results of this study not only demonstrate the need to create a completely safe analogue of sucralose, but may suggest a new way for doctors to influence T cells to fight autoimmune diseases.
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