Researchers at the University of Sydney developed unique protein capsules that could correctly correctly correct drugs, including toxic drugs used for chemotherapy, and damaged healthy tissues. Published in İş Magazine Angerwandte Chemie International Edition (Pain).
Dr. The team, led by Taylor Shishka and Associate Professor Yu Hyn Lau, was able to effectively upload a protein capsule – so -Consstreded capsules – with a widely used doxorubicin in cancer treatment. The resulting structure is collected from the same proteins and forms a stable global shell that protects treatment for demolition and leakage.
Previously, encapsulins can only be used to give molecules with a complex procedure for disassembly and re -assembly, which violates their stability. The new approach made it possible to start the installation of the capsule and avoid these problems after loading.
“This is possible for the first time to upload for capszing during the installation of the drug, and not after or after,” Shishka explained. “We actually collected a capsule with a” load “inside, and proved it using a fluorescent signal doxorubicin.”
The authors emphasize that this is only the first step. The next stage is to learn how to refer the protein capsules to the right cells, for example, to liver cells, if you need to treat the liver.
“We’ve gathered a car, now we need to learn how to manage,” he added.
Previously, scientists To create A molecule that selectively destroy dangerous bacteria without affecting useful ones.
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Source: Gazeta
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