Researchers from the Research Institute found that the German trias Pujol (Spain), the lack of HDAC11 protein in the body helps to preserve the muscle mass, improves healing after injury and increases overall muscle function. Research Results published Geroscience in scientific journal.
Sarcopenia – Loss of age of muscle mass and strength – seriously reduces the quality of life of the elderly. However, effective ways or treatment of preventing it is still limited. In order to find new therapeutic approaches, scientists examined the biological mechanisms of muscle aging in the old rodents model.
It turned out that the blocking of HDAC11 protein in the body slows down muscle atrophy, protects the reserve of muscle stem cells, improves the operation of neuromuscular compounds and activates the regeneration procedures. In addition, improvements have been observed in muscles with reduced HDAC11 levels, metabolism of fatty acids and a more suitable lipid profile.
The leading author of the study. Monika Suelves, “Our data allows us to see HDAC11 as Herogen – a gene that contributes to aging. We offer as a new therapeutic target to combat the sarcopenia,” he said.
Considering that HDAC11 inhibitors already exist, exploration may become the basis for creating drugs that slow down the weakening of age of the muscles and contribute to a healthier human age.
Previously named It is guaranteed that the method will delay old age.
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Source: Gazeta
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