Scientists have found a way to support resistance genes from bacteria to antibiotics 13: 56

Scientists from the University of Birmingham took an important step in the fight against antibiotic resistance, one of the most serious threats of health services of the 21st century. They deciphered the basic areas of DNA responsible for SO -CALLED, a process that allows you to remove antibiotic resistance genes from bacteria. Published in İş Magazine Nucleic Acids Research (Pomegranate).

Plasmids are small ring -shaped DNA molecules of bacteria that rapidly change useful genetic information. The problem is that through plasmids, the spread of genes that make bacteria resistant to drugs often spread.

Professor Chris Thomas of Bionauk Birmingham School has been examining the methods of “displacement” for years. The laboratory has developed effective multiple excavation plasmids (with many copies in each cage), which replaces dangerous plasmids and prevents bacteria from spreading stability. This technology is already patented.

However, to use such a method as probiotic – for example, it was necessary to transfer the system to “low -grade” plasmids in the form of an oral additive that could spread to the intestines. For effective work, scientists faced the fact that such plasmids should first be strengthened artificially. They called this phenomenon “strengthening”.

Everything is about the special features of the plasmid type F in E. coli, where his team works. Researchers have managed to correctly determine the DNA section required for successful displacement, and based on this, to create a completely new “therapeutic cassette oluşu working without amplification.

Now scientists focus on examining the spread of such plasmid into the intestines of animals. Professor Thomas Emin: These developments may become the basis of creating effective probiotics that can prevent the transmission of antibiotic resistance genes to humans.

Previously, scientists Created Virtual intestine to reveal the secrets of germs.