Dr. Korean Materials Institute. The research team, led by Ho Sang Zhon, developed an innovative technology that allows you to diagnose osteoarthritis and rheumatoid arthritis based on synovial fluid analysis, together with Holy Mary Hospital in Seoul. Published in İş Magazine Small.
According to studies, osteoarthritis symptoms live with more than 50% of people over 65 years of age and with a serious chronic illness that is sick with approximately 1 out of 100 people during life. Although the symptoms of the diseases are similar, their causes and treatment are different, so early definitive diagnosis is very important. So far, the diagnosis is based on an X -ray, MRI and blood tests, which is an expensive, long and always unknown process.
The synovial fluid is a viscous transparent substance that fills the joint cavity. It plays the role of natural lubrication, reduces friction between joint surfaces and nourishes the cartilage. A change in the composition of this fluid may show the development of various diseases of the joints, including arthritis.
Scientists focused on the work of the differences in metabolites – with products of chemical processes in the body as part of synovial fluid. They applied the advanced surface combination light scattering technology, which increases the optical signals of molecules millions of times. In this way, it was possible to determine the trace of the substances responsible for the development of arthritis.
In addition, the team developed a compact sensor on paper with gold nanoyaps that effectively absorb moisture and quickly analyze biological fluids.
In clinical studies on 120 patients, technology showed more than 94% accuracy in the diagnosis and distinction between osteoarthritis and rheumatoid arthritis. Determining the severity of rheumatoid arthritis reached more accuracy of more than 95%.
Ho Sang Zhon said: “Under commercialization, this technology will help to monitor the efficiency of the treatment not only in rapid diagnosis, but also in the future. In the future, we plan to expand its use for other diseases.”
Previously, scientists for the first time Raised New teeth using a combination of human and pig cells.
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Source: Gazeta

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