The International team of scientists discovered a promising connection to fight with Gonococcus (Neisseria Gonorrhoeae), a dangerous causal agent of Gonore, which rapidly resisting antibiotics. Research Results published In Nature Microbiology magazine.
Researchers from the University of Constanta and the University of Vienna, a new class of substance – alkylchinolones, natural molecules used by bacteria to fight each other. Especially interesting, synthetic option-2-nonni-4-hinolone-n-oxide (NQNO).
Experiments have shown that NQNO violated the electron transfer chain in Gonococcus cells, causes severe internal stress and activates the bacterial self -providing program. It also turned out to be safe for human cells and friendly microflora.
In animal experiments, the new therapy method has shown high efficiency. Scientists also managed to improve NQNO’s features using chemical modification.
Neisseria Gonorrhoeae is included in the World Health Organization in the list of priority pathogens due to its ability to rapidly resist treatment. A new discovery can be an important step against the background of the spread of hard -production strains in the fight against this infection.
Earlier intestinal bacteria It turned out to be It can cause blood cancer.
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Source: Gazeta
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