German scientists from the University of Bonn and the German Neurodi -Generative Diseases Center have revealed the mechanism to improve spastic parapolege of 15th type – a rare hereditary disease that is progressive in children. The study was published scientifically broadcasting Journal of Experimental Medicine (JEM).
The team found that an extreme reaction of the immune system, which causes damage to neurons, played an important role in the emergence of the disease.
Scientists used genetically modified mice in the SPG15 gene. By applying advanced visualization methods, they were able to monitor the interaction between different immune cells at the level of separate cells.
Professor Elvira, one of the masses, said, ik We learned that micro -microitis – immune cells of the brain – even before the destruction of neurons, ”he said.
These cells begin to spread signal molecules that attract cytotoxic T cells from the bone marrow, which triggers an inflammatory processes.
According to researchers, immunosuppressive drugs can potentially slow the progression of the disease if used in early stages.
The data obtained are particularly valuable because similar mechanisms can participate in the development of Alzheimer’s disease and other neurodegenerative diseases.
Early in Japan Healed Stem cell paralyzed patient.
What are you thinking?
Source: Gazeta
Barbara Dickson is a seasoned writer for “Social Bites”. She keeps readers informed on the latest news and trends, providing in-depth coverage and analysis on a variety of topics.