Dutch scientists from Radbaud University Medical Center made a breakthrough in the treatment of sepsis, which is a dangerous situation in the intensive care units, 20% of patients. Multiple sclerosis interferon has found that the present drug for beta can restore the function of immune cells that are paralyzed with this disease. The study was published scientifically magazine Nature immunology (Natimmun).
Sepsis, also known as blood poisoning, has long been accepted as a result of a hyperactive immune response. However, scientists have now proved that the opposite situation is a danger – immune paralysis when protective cells stopped fighting infection.
Huyite researcher, “Immunities paralyzed patients can not overcome the current infection and, for example, become vulnerable to new attacks such as fungi,” he said.
As part of the experiment, the participants were inserted by endotoxins (components of lifeless bacteria) and caused a controlled immune reaction. Later, with the help of advanced technologies, scientists followed all the stages of the response from a violent reaction to paralyzes. The monocytes were focused – the switch that stops normal maturation during sepsis immune cells.
Interferon showed surprising results in the beta laboratory. The paralyzed monocytes under the action began to mature normally and regained their ability to fight infections.
Considering that all three patients with sepsis do not survive in intensive care and that survivors often suffer from long -term results, discovery is particularly important.
Previously, researchers To create A new treatment of acute lung damage.
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Source: Gazeta
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