American scientists from New York University Faculty of Medicine and other science centers found an important immune cell group responsible for tolerance to food proteins. The discovery explains why the immune system does not attack harmless substances and can become the basis of new methods of treating allergies. The study was published scientifically magazine Nature.
The team found that special toleogenic dendritic cells in the intestine produce immune tolerance thanks to Rorrance and PRDM16 proteins. They prevent inflammatory reactions to food and useful bacteria that confirm experiments on mice: asthma and food allergies developed in rodents in the absence of these cells.
According to the authors of the study, the detection of the mechanism will create treatment for patients with allergies through the activation of these cells. Discovery can also help fight against Crohn and other autoimmune diseases. The approach should also work in public, because an analogs of these cells were found in a person.
Previously, scientists To create Natural substance that weakens the symptoms of allergies.
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Source: Gazeta
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