Scientists developed a “metal detector” to determine dangerous cancer forms 13:46

Scientists from the University of Cambridge have developed the Prrdect algorithm, a powerful tool that can define tumors with weakened DNA restoration mechanisms and make them more sensitive to treatment. Published in İş Magazine Nature genetics.

The authors analyzed the full genomes of 4,775 tumors, which consist of seven types of cancers, including pulmonary, brain, skin, stomach and intestine. All data were obtained as part of a large -scale project of 100,000 genome projects.

The main attention in the study is paid to So -Conred Insert mutations – the extraction of attachments and the extraction of DNA fragments. Researchers have found that certain characteristic patterns of such mutations show malfunctions in the latest reference heal of DNA (PRD). These faults reduce the resistance of the tumor to treatment and increase the sensitivity of immune treatment.

Based on these data, a PRRDETECT was created – an algorithm that can correctly “monitor tumors with a PRRD like a metal detector responding to the vulnerability. This leads to more personalized treatment strategies, especially for patients with cancerous patients who are difficult to deliver to treatment.

Professor Serena Nick-Zin, the leading author of the study, stressed that the development of technology and genomic sequence became as suitable as a blood test or MRI. However, for genetic use in clinical practice, there is a need for algorithms to give doctors useful and applicable information about treatment estimation and choice.

“PRRRETECT allows us to understand which tumors are vulnerable, so they are treated. This is particularly important for fatal cancer forms such as lung or brain cancer,” he said.

According to scientists, the development of the prrdetct algorithm has become another step to ensure that genomic technologies turn into daily clinical practices.

Previously, scientists for the first time Created A detailed map of human cells.