A group of international scientists from a Child Consortium (PCGC) has identified 60 key genes, mutations that significantly increased the risk of congenital heart defects (VPS). The study was published scientifically magazine National Academy of Sciences (PNA) procedures.
Experts analyzed the data of more than 11,000 patients and found that approximately 60% of VPS cases were associated with mutations in 60 gends, and half of them had a specific connection with certain types of pathologies.
It was also known that 5% of mutations were clinically transmitted from healthy parents, which explains the family cases of VPs in the absence of the symptoms of the old generation.
In families where both parents are carriers of recessive mutations, the risk of VPS in a child increases seven times.
In addition, more than half of the genes from the list (37) are associated with other disorders of autism and the development of the nervous system.
According to researchers, discovery can improve early scanning of children with VP. The genetic test of newborns will define the accompanying risks (eg arrhythmias or autism) until the emergence of symptoms.
Scientists emphasize that 10 of 60 genes participate in the modification of chromatin, a process that regulates the activity of other genes. This paves new ways for the therapy for epigenetic correction.
Previously, researchers learnedChildren born in front of the program are less active in adult age.
What are you thinking?
Source: Gazeta
Barbara Dickson is a seasoned writer for “Social Bites”. She keeps readers informed on the latest news and trends, providing in-depth coverage and analysis on a variety of topics.