I found a way to estimate the dangerous side effects of cancer treatment 12:58

Scientists from the University of Kyusu revealed specific spine fluid proteins, where you can evaluate the risk of failure in the operation of immune and nervous systems after the Car-T-therapy of cancer. Research Results published In the Journal of Leukemia.

For CAR-T-therapy, re-program the patient to be more successful in the cancer cells, so that they can destroy them. This technique is effective, however, it is associated with the risk of serious side effects, including immuno -Arabian neurotoxicity syndrome, which may lead to inflammation of the central nervous system.

The two can manifest themselves as more serious conditions such as headache and disorder in the brain, cramps or bleeding. The frequency of icons after CAR-T-therapy is approximately 64%.

To understand what the risk of the dangerous consequences of Car-t-therapy, scientists analyzed the proteins of 29 patients with non-inflict lymphoma (blood cancer type) of non-irrigation before starting treatment. When developing 11, 18 had no symptoms of neurotoxicity.

The researchers identified 46 proteins with a significant level of level in patients with seconds. Among these, two proteins – C1RL and Fuc2 – showed the greatest importance to estimate the risk of damaging the nervous system. By measuring the ratio of these proteins, scientists were able to predict the likelihood of developing neurotoxicity in patients with high accuracy.

The new prognostic method was successfully tested in the second group of 10 patients. However, scientists warn that despite high accuracy, the results require approval in a larger example.

If more research is successful, the evaluation of C1RL and FUC2 levels will help doctors diagnose ICANs before the patient’s condition worsens. Discovery can also contribute to the development of drugs that reduce the risk of neurotoxicity.

Previously, scientists learnedthat a drug for diabetes can be protected against blood cancer.