American scientists from the University of California in San Francisco have discovered a new way to combat cancer by targeting the increasing MyC protein in 70% of cases between all kinds of cancer. The study was published scientifically magazine Nature Cell Biology (NCB).
Opened in the 1970s, MYC plays an important role in tumor growth. However, there was still no way to prevent directly. UCSF scientists decided to approach the problem differently by focusing on MYC production mechanism.
Using the CRISPRI method, they found that the RBM42 protein controls the broadcasting process of Ribosomes Ribosomes. CRISPRI is a modified version of CRISPR-CAS technology used to suppress genes without changing DNA itself.
When RBM42 was blocked in pancreas cancer cells, MyC production stopped and tumors stopped growth.
David Rudero, the senior writer of the study, said, “Now we understand the mechanism that controls the MyC level, we have a chance to stop.”
Mouse experiments confirmed that the removal of RBM42 has stopped the growth of tumors. Scientists plan to develop drugs that block RBM42, which may be a breakthrough in the treatment of aggressive cancer types.
Previously, Russian scientists saidHow cancer is detected in early stages.
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Source: Gazeta
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