Finnish scientists from the University of Helsinki have discovered the cause of health problems in some babies born through in vitro fertilization (IVF). The research was published in the scientific journal magazine Communication Medicine (CommsMed).
Experts have concluded that the in vitro fertilization procedure affects the epigenetics of the placenta. The team analyzed DNA and epigenetic markers in the placental tissues of women using assisted reproductive technologies.
Scientists found that unfrozen embryos were more likely to have changes in gene expression than frozen embryos. This may be due to exposure to hormones at a key point in development during the formation of epigenetic markers.
Additionally, the researchers identified three genes (TRIM28, NOTCH3, and DLK1) that were differentially expressed in fresh embryonic placentas. The activity of these genes was associated with differences in birth weight and length compared to controls.
According to experts, changes in genes may explain some epigenetic abnormalities associated with low body weight and metabolic disorders in babies born through in vitro fertilization. Additionally, some of these children may have an increased risk of developing heart defects in the future.
The authors of the report emphasized that the vast majority of in vitro fertilization babies are completely healthy, and the likelihood of these problems occurring is very low.
Previously in the light in Peru appeared The first child conceived using a new in vitro fertilization method.
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Source: Gazeta
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