Scientists at the University of Nottingham found that blood sugar and weight loss drugs like Ozempic help reduce drinking by targeting the reward center of the brain. Research results It was published In the journal eClinicalMedicine.
The team extensively reviewed existing studies to examine the effects of GLP-1 receptor agonists on alcohol use as well as changes in alcohol-related behaviors.
Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of antidiabetic drugs that have gained popularity in recent years. GLP-1 is a peptide synthesized in the human gastrointestinal tract. Mimicking its release with drugs stimulates insulin production, reduces glucose absorption in the gastrointestinal tract, suppresses hunger and slows the digestion of food.
Scientists evaluated the results of six studies involving a total of 88,190 people. Of these, 38,740 (43.9%) participants received GLP-1.
It appears that these types of diabetes medications may be effective in reducing alcohol consumption by potentially targeting the pleasure center of the brain, especially in people with a BMI over 30. In one important study, the drug Exenatide had no significant effect on reducing alcohol consumption. generally for six months, but some positive results were observed in obese people. Another study found that people who took the drug Dulaglutide were 29% more likely to reduce their alcohol consumption than those who took a placebo.
Observational studies have shown that individuals taking GLP-1 have fewer alcohol-related health problems.
Weight loss drugs may provide the greatest benefit to patients who are both overweight and suffer from alcohol addiction, scientists say. However, additional research is needed to calculate the optimal dosage and use regimen.
Previously It was published The first global analysis of global diabetes rates.
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Source: Gazeta

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