Researchers from Queen Mary University of London found that genetically determined heart shape may affect the risk of cardiovascular disease. Research results It was published In the journal Nature Communications.
A new study by scientists has become the first to examine the genetic basis of the shape of the heart’s right and left ventricles using advanced 3D imaging and machine learning technologies. Previous research has focused primarily on the size and volume of individual rooms, limiting understanding of how structural changes may affect disease risk.
Researchers used MRI images of the hearts of more than 40,000 people. The data was provided by UK Biobank, a large-scale repository containing genetic and medical information on half a million volunteers. Based on these data, 3D models of the heart’s ventricles were created, and then, using statistical analysis, 11 shape parameters were determined that reflect the main differences in the structure of the organ.
Additional genetic analysis identified 45 genomic regions associated with changes in the structure of the organ. According to scientists, the information obtained could significantly change the approach to assessing the risk of cardiovascular diseases, one of the leading causes of death worldwide.
Previous scientists saidHow to reduce the risk of arrhythmia by 11%.
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Source: Gazeta

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