Scientists from the University of California, Los Angeles, have grown blood stem cells in the laboratory for the first time. This achievement opens up new possibilities for treating various diseases of the blood and immune system. Results It was published In the journal Nature Biotechnology.
Hematopoietic cells, also known as hematopoietic stem cells, have the ability to develop into various blood cells. Previously, they could only be obtained from bone marrow, umbilical cord blood, or peripheral blood.
Scientists are focusing on finding ways to create blood stem cells in the laboratory. This would significantly simplify the treatment process for patients with blood diseases.
Scientists used pluripotent stem cells that can develop into any cell in the body. Using CRISPR technology, they activated certain genes responsible for the development of hematopoietic stem cells. As a result, it was possible to grow cells that can form all types of blood cells, including red blood cells, white blood cells, and platelets.
The discovery could revolutionize treatments for diseases such as leukemia, lymphoma and sickle cell disease. Many patients currently require bone marrow transplants, but finding a suitable donor is often a challenge. Growing blood stem cells in the laboratory could solve the problem of donor shortages and make treatment more accessible.
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Source: Gazeta
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