An international team of scientists from Finland and China have created a self-healing hydrogel-based dressing designed to treat diabetic wounds. The research was published in the scientific journal magazine Nano-Micro Letters (NML).
The team used structured microspheres composed of methacrylated hyaluronic acid, methacrylated silk fibroin, and black phosphorus quantum dots.
The microspheres are loaded with melittin (an antibacterial substance found in bee venom) and vascular endothelial growth factor. The authors noted that the microsphere system demonstrates the potential for controlled drug release and effective wound healing.
Scientists evaluated the wound healing efficacy of composite microspheres (CMP) in a rat model of chronic diabetic wound infection. As experiments showed, the medicated microspheres increased collagen formation and accelerated the growth of new blood vessels in the affected tissues.
Treatment of ulcers with CMP combined with infrared light irradiation showed superior regeneration results, the researchers said.
Earlier scientists learned Highlight bacteria in patients’ diabetic wounds.
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Source: Gazeta
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