Scientists from Rutgers University found that chronic fatigue may be associated with changes in the composition of the cerebrospinal fluid. The study was published on: Annals of Medicine.
There has long been debate about whether fibromyalgia and chronic fatigue syndrome, which share neurological symptoms, are separate diseases of the central nervous system or related diseases. The source of both conditions is unknown and causes fatigue that can last for months or years. In fibromyalgia, the patient also suffers from severe muscle pain that is not associated with inflammation.
Doctors used mass spectrometry to examine proteins in the cerebrospinal fluid of 30 patients. Half of the patients had chronic fatigue syndrome, and the others had chronic fatigue syndrome and fibromyalgia. Of the 2083 proteins measured, 1789 were present in both samples. This may mean that the diseases are similar in nature.
Advances in mass spectrometric analysis have facilitated the research, the authors said. Previously, large amounts of cerebrospinal fluid were required to perform such tests, but advanced methods allow smaller amounts of sample to be used and many proteins to be analyzed simultaneously.
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Source: Gazeta
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