Scientists have identified genetic changes because cancer in one breast can contribute to the development of a similar disease in another breast. About informs Swimsuit clinic.
The study used data from 15,104 women followed by the CARRIERS cancer risk assessment consortium. The researchers found that patients who carry a germline mutation in the BRCA1, BRCA2 or CHEK2 genes have at least twice the risk of developing cancer in both breasts, known as contralateral breast cancer.
In contrast, patients carrying germline mutations in the ATM gene did not have an increased risk of developing such cancers. Among carriers of the PALB2 mutation, the risk of contralateral breast cancer was significantly increased only if the disease was estrogen negative.
In addition, the effect of genetic susceptibility to contralateral cancer was stronger in premenopausal women at the time of diagnosis. The race of the patients does not matter.
The authors hope their findings will help predict breast cancer development more accurately and act proactively to protect the second mammary gland, if possible.
Child sex selection and human cloning: What do you think about the controversial issues of bioethics? To go past interview “socialbites.ca”.
Source: Gazeta
Barbara Dickson is a seasoned writer for “Social Bites”. She keeps readers informed on the latest news and trends, providing in-depth coverage and analysis on a variety of topics.