Nanographic, also called nanolipophilization, is an advanced aesthetic medicine technique that uses a patient’s own fat tissue processed into a nanolipid emulsion and then grafted to address visible signs of aging. In clinical reports from DMC Innovation Medicine, Dr. Rose Gerliiani, a plastic surgeon and dermatologist, explains that the process begins with harvesting small amounts of fat, which are then refined into a uniform, highly purified emulsion. The goal is not just to fill; the aim is to deliver microdoses that work with the skin’s biology to promote healthier, more resilient tissue. [Citation: Dr. Rose Gerliiani, DMC Innovation Medicine]
According to Dr. Gerliiani, nanographic therapy can smooth fine and deeper wrinkles, including periorbital lines and nasolabial folds, restore mid-face volume, and reduce dark circles under the eyes. Beyond the cheeks, the technique may address scar tissue and skin changes on the neck, décolletage, and even the hands. It also has potential to correct mild facial asymmetry. The report emphasizes a natural rebuilding of tissue rather than a blunt, siloed fill. [Citation: Dr. Gerliiani]
Developed as an improved version of classic lipofilling, nanography uses a highly purified fat emulsion that is processed into a nanometer-scale preparation. This refinement involves filtration steps and gentle emulsification to create a stable, bioactive carrier. In practice, the nanographic solution is designed to integrate with the superficial layers of the skin and underlying tissues, supporting subtle remodeling and renewal. [Citation: Dr. Gerliiani]
One of the main ideas behind nanography is regeneration rather than simply increasing volume. The approach leverages cellular activity within the graft, including growth factors and stem cells, to encourage the skin to renew itself from within. This regenerative emphasis is what helps minimize obvious swelling or a heavy, unnatural look, especially around delicate areas. [Citation: Dr. Gerliiani]
When traditional lipofilling relies on larger fat deposits to restore volume, the nanographic emulsion is enriched with stromal-vascular fraction SVF and adipose-derived stem cells. This enrichment allows the material to be placed more superficially while still promoting durable tissue remodeling. The result can feel lighter on the surface while supporting ongoing regeneration beneath. [Citation: Dr. Gerliiani]
Dermatology specialists note that nanography reduces the risk of lump formation in sensitive zones around the eyes, the nasolabial region, and other fine facial areas. The more even distribution of the emulsion helps avoid conspicuous irregularities, which is a common concern in facial rejuvenation. According to Dr. Gerliiani, careful technique and the SVF-rich emulsion contribute to smoother, more uniform outcomes. [Citation: Dr. Gerliiani]
Gerliiani points out several advantages of this technique. Among them is precision: the use of ultra-thin or ultra-thick cannulas allows clinicians to address tiny flaws with minimal tissue disruption. The distribution of the emulsion tends to be even, which supports a natural look as the skin reconstitutes itself. Patients often experience less downtime and a more harmonious result as gravity and tissue dynamics resume a balanced state. [Citation: Dr. Gerliiani]
In addition to external effects, nanography is said to provoke positive internal changes. Biostimulation and the activation of regenerative processes through stem cells and growth factors are reported to occur as the nanographic emulsion interacts with the skin’s microenvironment. These internal changes contribute to continued improvement beyond the initial contouring. [Citation: Dr. Gerliiani]
Recovery after nanography is typically rapid. Swelling and redness tend to subside within two to three days, and many patients return to normal activities soon after treatment. Importantly, the effects can persist for up to several years, thanks to the high survival rate of the transplanted cells and ongoing tissue remodeling. The clinical experience shared by Gerliiani underscores the potential for durable, natural-looking rejuvenation. [Citation: Dr. Gerliiani]
Cosmetology and dermatology specialists emphasize that the technique is compatible with broader anti-aging strategies. For instance, Alexander Bykanov, a cosmetologist and dermatology practitioner, notes that combining nanography with tailored skincare routines can help preserve facial youth over time. He stresses the importance of sun protection, hydration, and gentle skin care as supporting measures rather than substitutes for regenerative procedures. [Citation: Alexander Bykanov]
Seasonal skin care also plays a role. A dermatologist from the clinic discusses skincare considerations for spring, including lighter textures, sun protection, and ongoing maintenance to extend the effects of regenerative procedures. The focus is on preserving skin health as climate and daily routines shift, ensuring that rejuvenation endures through seasonal changes. [Citation: Clinic Dermatology Specialist]
Overall, nanographic therapy represents a regenerative approach to facial aesthetics, blending autologous tissue with advanced processing to support long-term skin quality and resilience. Clinicians emphasize individualized treatment plans, realistic expectations, and careful follow-up to maximize outcomes. [Citation: Clinical Guidance]