Researchers from the University of Dundee (England) have shown that the effectiveness of drugs for hypertension does not depend on the time of administration, which contradicts previous studies. Results presented At the 2022 Congress of the European Society of Cardiology.
The scientists followed more than 21,000 patients with high blood pressure for five years. Half of the participants took the pills in the morning and the other half in the evening. The mean age of the participants was 65, 58% were male and 98% were of European descent. The median follow-up was 5.2 years, although some patients participated in the study for more than nine years. The frequency of hospitalization for underlying cardiovascular diseases associated with hypertension was approximately the same in both groups.
Nighttime blood pressure is a better predictor of clinical outcome than daytime blood pressure. The Hygia2 study has previously shown that evening high blood pressure medications are more effective. New data refute this conclusion. The authors emphasize that people with high blood pressure should regularly take antihypertensive medications at a time convenient for them.